MFG-E8 Regulates Microglial Phagocytosis of Apoptotic Neurons

Phagocytosis is an essential mechanism for clearance of pathogens, dying cells, and other unwanted debris in order to maintain tissue health in the body. Macrophages execute this process in the peripheral immune system but in the brain microglia act as resident macrophages to accomplish this functio...

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Veröffentlicht in:	Journal of neuroimmune pharmacology 2008-12, Vol.3 (4), p.246-256
Hauptverfasser:	Fuller, Abby D., Van Eldik, Linda J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - metabolism Alzheimer Disease - pathology Animals Antigens, Surface - genetics Antigens, Surface - metabolism Apoptosis Apoptosis - physiology Biomedical and Life Sciences Biomedicine Blotting, Western Cell Biology Cell Line Chemokine CX3CL1 - metabolism Coculture Techniques Disease Models, Animal Humans Image Processing, Computer-Assisted Immune system Immunology Mice Mice, Transgenic Microglia - metabolism Milk Proteins - genetics Milk Proteins - metabolism Neurons - pathology Neurosciences Original Original Article Phagocytosis - physiology Pharmacology/Toxicology Virology
Online-Zugang:	Volltext
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