Maternal Bisphenol A Exposure Promotes the Development of Experimental Asthma in Mouse Pups

Background: We recently reported that various environmental estrogens induce mast cell degranulation and enhance IgE-mediated release of allergic mediators in vitro. Objectives: We hypothesized that environmental estrogens would enhance allergic sensitization as well as bronchial inflammation and re...

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Veröffentlicht in:	Environmental health perspectives 2010-02, Vol.118 (2), p.273-277
Hauptverfasser:	Midoro-Horiuti, Terumi, Tiwari, Ruby, Watson, Cheryl S., Goldblum, Randall M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergies Animals Animals, Newborn Asthma Asthma - chemically induced Asthma - immunology Benzhydryl Compounds Biological and medical sciences Bisphenol-A Bisphenols Bronchial Hyperreactivity - chemically induced Chronic obstructive pulmonary disease, asthma Environmental health Enzyme-Linked Immunosorbent Assay Estrogens Female Health aspects Immunoglobulin E Lung - drug effects Lung - immunology Mast cells Maternal Exposure - adverse effects Medical sciences Mice Mice, Inbred BALB C Ova Phenols - adverse effects Phenols - immunology Physiological aspects Pneumology Pregnancy Risk factors Sensitization T lymphocytes
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