NSAID‐induced antral ulcers are associated with distinct changes in mucosal gene expression

Summary Background The basis for individual variation in gastroduodenal vulnerability to NSAIDs is not well understood. Aim To assess whether a gene expression signature is associated with susceptibility to gastroduodenal ulcerations. Methods Twenty‐five Helicobacter pylori negative adults were t...

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Veröffentlicht in:	Alimentary pharmacology & therapeutics 2009-07, Vol.30 (1), p.71-81
Hauptverfasser:	DESAI, J. C., GOO, T., FUKATA, M., SANYAL, S., DIKMAN, A., MILLER, K., COHEN, L., BROOKS, A., WANG, Q., ABREU, M. T., AISENBERG, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anti-Inflammatory Agents, Non-Steroidal - adverse effects Anti-Inflammatory Agents, Non-Steroidal - pharmacology Biological and medical sciences Digestive system Female Gastric Mucosa - drug effects Gastroenterology. Liver. Pancreas. Abdomen Gene Expression - drug effects Helicobacter pylori Humans Male Medical sciences Middle Aged Naproxen - adverse effects Naproxen - pharmacology Peptic Ulcer - chemically induced Pharmacology. Drug treatments
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