Translational activation of rpoS mRNA by the non-coding RNA DsrA and Hfq does not require ribosome binding

At low temperature, translational activation of rpoS mRNA, encoding the stationary phase sigma-factor, σS, involves the small regulatory RNA (sRNA) DsrA and the RNA chaperone Hfq. The Hfq-mediated DsrA-rpoS interaction relieves an intramolecular secondary structure that impedes ribosome access to th...

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Veröffentlicht in:	Nucleic acids research 2010-03, Vol.38 (4), p.1284-1293
Hauptverfasser:	Večerek, Branislav, Beich-Frandsen, Mads, Resch, Armin, Bläsi, Udo
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - biosynthesis Bacterial Proteins - genetics Blotting, Western Cytoplasm - chemistry Escherichia coli - genetics Escherichia coli - metabolism Escherichia coli Proteins - analysis Escherichia coli Proteins - biosynthesis Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism Gene Expression Regulation, Bacterial Host Factor 1 Protein - analysis Host Factor 1 Protein - metabolism Molecular Biology Protein Biosynthesis Ribosomal Proteins - metabolism Ribosome Subunits, Small, Bacterial - metabolism Ribosomes - metabolism RNA, Messenger - chemistry RNA, Small Untranslated RNA, Untranslated - metabolism Sigma Factor - biosynthesis Sigma Factor - genetics
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