Embryonic Stem Cell-Derived Neural Precursor Grafts for Treatment of Temporal Lobe Epilepsy

Complex partial seizures arising from mesial temporal lobe structures are a defining feature of mesial temporal lobe epilepsy (TLE). For many TLE patients, there is an initial traumatic head injury that is the precipitating cause of epilepsy. Severe TLE can be associated with neuropathological chang...

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Veröffentlicht in:	Neurotherapeutics 2009-04, Vol.6 (2), p.263-277
Hauptverfasser:	Maisano, Xu, Carpentino, Joseph, Becker, Sandy, Lanza, Robert, Aaron, Gloster, Grabel, Laura, Naegele, Janice R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine cell therapy Embryonic Stem Cells - transplantation Epilepsy Epilepsy, Temporal Lobe - therapy GABA GFP hilus hippocampus Humans interneuron Neurobiology Neurology Neurons - cytology Neurons - transplantation Neurosciences Neurosurgery Seizures sonic hedgehog Sox1 Stem Cell Transplantation - methods Stem Cell Transplantation - trends Stem cells Theme 2: Cell Therapy
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