Assembly of a β2-adrenergic receptor-GluR1 signalling complex for localized cAMP signalling

Central noradrenergic signalling mediates arousal and facilitates learning through unknown molecular mechanisms. Here, we show that the β 2 ‐adrenergic receptor (β 2 AR), the trimeric G s protein, adenylyl cyclase, and PKA form a signalling complex with the AMPA‐type glutamate receptor subunit GluR1...

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Veröffentlicht in:	The EMBO journal 2010-01, Vol.29 (2), p.482-495
Hauptverfasser:	Joiner, Mei-ling A, Lisé, Marie-France, Yuen, Eunice Y, Kam, Angel Y F, Zhang, Mingxu, Hall, Duane D, Malik, Zulfiqar A, Qian, Hai, Chen, Yucui, Ulrich, Jason D, Burette, Alain C, Weinberg, Richard J, Law, Ping-Yee, El-Husseini, Alaa, Yan, Zhen, Hell, Johannes W
Format:	Artikel
Sprache:	eng
Schlagworte:	adrenergic AMPA EMBO27 EMBO37 localized signalling
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