YabA of Bacillus subtilis controls DnaA-mediated replication initiation but not the transcriptional response to replication stress

yabA encodes a negative regulator of replication initiation in Bacillus subtilis and homologues are found in many other Gram-positive species. YabA interacts with the β-processivity clamp (DnaN) of DNA polymerase and with the replication initiator and transcription factor DnaA. Because of these inte...

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Veröffentlicht in:	Molecular microbiology 2009-10, Vol.74 (2), p.454-466
Hauptverfasser:	Goranov, Alexi I, Breier, Adam M, Merrikh, Houra, Grossman, Alan D
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacillus subtilis Bacillus subtilis - genetics Bacillus subtilis - metabolism Bacterial Proteins - genetics Bacterial Proteins - metabolism Bacteriology Biological and medical sciences Deoxyribonucleic acid DNA DNA Replication DNA, Bacterial - biosynthesis DNA-Directed DNA Polymerase - genetics DNA-Directed DNA Polymerase - metabolism Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation, Bacterial Gram-positive bacteria Microbiology Miscellaneous Oligonucleotide Array Sequence Analysis Origin Recognition Complex Proteins RNA, Messenger - metabolism Transcription, Genetic
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