Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing

Eukaryotic pre-mRNA splicing is a complex process requiring the precise timing and action of >100 trans-acting factors. It has been known for some time that the two steps of splicing chemistry require three DEAH-box RNA helicase-like proteins; however, their mechanism of action at these steps has...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	RNA (Cambridge) 2010-03, Vol.16 (3), p.516-528
Hauptverfasser:	Lardelli, Rea M, Thompson, James X, Yates, 3rd, John R, Stevens, Scott W
Format:	Artikel
Sprache:	eng
Schlagworte:	DEAD-box RNA Helicases - metabolism Hydroxides - metabolism Introns Models, Chemical Ribonucleoprotein, U2 Small Nuclear - metabolism RNA Precursors - chemistry RNA Precursors - metabolism RNA Splicing Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - metabolism Spliceosomes - chemistry Spliceosomes - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!