novel choline cotransporter sequestration compartment in cholinergic neurons revealed by selective endosomal ablation

J. Neurochem. (2010) 112, 1295-1304. The sodium-dependent, high affinity choline transporter - choline cotransporter - (ChCoT, aka: cho-1, CHT1, CHT) undergoes constitutive and regulated trafficking between the plasma membrane and cytoplasmic compartments. The pathways and regulatory mechanisms of t...

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Veröffentlicht in:	Journal of neurochemistry 2010-03, Vol.112 (5), p.1295-1304
Hauptverfasser:	Ivy, Michael T, Newkirk, Robert F, Wang, Yilun, Townsel, James G
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Techniques - methods Ageing, cell death Animals Binding sites Biochemistry Biological and medical sciences Cell Membrane - metabolism Cell physiology Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Choline - metabolism choline transport Cholinergic Agents - metabolism compartmental ablation Endocytosis Endosomes - physiology Female Fundamental and applied biological sciences. Psychology Hemicholinium 3 - metabolism Horseradish Peroxidase - metabolism Horseshoe Crabs Male Membrane Transport Proteins - metabolism Membranes Molecular and cellular biology Neurology Neurons - cytology Neurons - physiology Plasma Potassium Chloride - metabolism Protein Binding Protein Transport - physiology recruitment Subcellular Fractions - physiology Time Factors transporter trafficking Tritium - metabolism Vertebrates: nervous system and sense organs
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