Nonlocal Interactions Are Responsible for Tertiary Structure Formation in Staphylococcal Nuclease

Rapid molecular collapse mediated by nonlocal interactions is believed to be a crucial event for protein folding. To investigate the role of nonlocal interactions in tertiary structure formation, we performed a nonlocal interaction substitution mutation analysis on staphylococcal nuclease (SNase). Y...

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Veröffentlicht in:Biophysical journal 2010-02, Vol.98 (4), p.678-686
Hauptverfasser: Kato, Shingo, Kamikubo, Hironari, Hirano, Satoshi, Yamazaki, Yoichi, Kataoka, Mikio
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Sprache:eng
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