Thermo- and Mesostabilizing Protein Interactions Identified by Temperature-Dependent Statistical Potentials

The goal of controlling protein thermostability is tackled here through establishing, by in silico analyses, the relative weight of residue-residue interactions in proteins as a function of temperature. We have designed for that purpose a (melting-) temperature-dependent, statistical distance potent...

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Veröffentlicht in:Biophysical journal 2010-02, Vol.98 (4), p.667-677
Hauptverfasser: Folch, Benjamin, Dehouck, Yves, Rooman, Marianne
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Sprache:eng
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