Localized topological changes of the plasma membrane upon exocytosis visualized by polarized TIRFM

Total internal reflection fluorescence microscopy (TIRFM) images the plasma membrane-cytosol interface and has allowed insights into the behavior of individual secretory granules before and during exocytosis. Much less is known about the dynamics of the other partner in exocytosis, the plasma membra...

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Veröffentlicht in:	The Journal of cell biology 2010-02, Vol.188 (3), p.415-428
Hauptverfasser:	Anantharam, Arun, Onoa, Bibiana, Edwards, Robert H, Holz, Ronald W, Axelrod, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal glands Animals Blood Cattle Cell Membrane - metabolism Cell membranes Cells Chromaffin cells Chromaffin Cells - cytology Chromaffin Cells - metabolism Cytosol - metabolism Dynamins - metabolism Endocytosis Endocytosis - physiology Exocytosis Exocytosis - physiology Fluorescence Geometric planes Mammals Membrane Fusion - physiology Membranes Memory interference Microscopy, Fluorescence P branes Secretory Vesicles - metabolism Simulation Sine function Topology
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