Iron:An emerging factor in colorectal carcinogenesis

The carcinogenic potential of iron in colorectal cancer(CRC) is not fully understood.Iron is able to undergo reduction and oxidation,making it important in many physiological processes.This inherent redox property of iron,however,also renders it toxic when it is present in excess.Iron-mediated gener...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2010-02, Vol.16 (6), p.663-672
Hauptverfasser:	Chua, Anita C G, Klopcic, Borut, Lawrance, Ian C, Olynyk, John K, Trinder, Debbie
Format:	Artikel
Sprache:	eng
Schlagworte:	Colorectal Neoplasms - etiology Colorectal Neoplasms - physiopathology Genomic Instability - physiology Humans Inflammation - physiopathology Iron - physiology Oxidative Stress - physiology
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