Toxins Hha and CspD and small RNA regulator Hfq are involved in persister cell formation through MqsR in Escherichia coli

Persisters are cells which evade stresses like antibiotics and which are characterized by reduced metabolism and a lack of genetic alterations required to achieve this state. We showed previously that MqsR and MqsA of Escherichia coli are a toxin–antitoxin pair that influence cell physiology (e.g.,...

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Veröffentlicht in:	Biochemical and biophysical research communications 2010-01, Vol.391 (1), p.209-213
Hauptverfasser:	Kim, Younghoon, Wood, Thomas K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Bacterial Toxins - genetics Bacterial Toxins - metabolism CspD DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Escherichia coli Escherichia coli - drug effects Escherichia coli - genetics Escherichia coli - physiology Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism Gene Deletion Gene Expression Profiling Heat-Shock Proteins - genetics Heat-Shock Proteins - metabolism Hfq Hha Host Factor 1 Protein - genetics Host Factor 1 Protein - metabolism MqsR Persister formation RNA - metabolism Stress, Physiological
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