Basal Cerebral Metabolism May Modulate the Cognitive Effects of Aβ in Mild Cognitive Impairment: An Example of Brain Reserve

Inverse correlations between amyloid-β (Aβ) load measured by Pittsburgh Compound-B (PiB) positron emission tomography (PET) and cerebral metabolism using [ 18 F]fluoro-2-deoxy- d -glucose (FDG) in Alzheimer's disease (AD) patients, suggest local Aβ-induced metabolic insults. However, this relat...

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Veröffentlicht in:	The Journal of neuroscience 2009-11, Vol.29 (47), p.14770-14778
Hauptverfasser:	Cohen, Ann D., Price, Julie C., Weissfeld, Lisa A., James, Jeffrey, Rosario, Bedda L., Bi, Wenzhu, Nebes, Robert D., Saxton, Judith A., Snitz, Beth E., Aizenstein, Howard A., Wolk, David A., DeKosky, Steven T., Mathis, Chester A., Klunk, William E.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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