Seroprevalence of hepatitis B virus, hepatitis C virus and GB virus-C infections in Siberia

We studied the seroprevalence of hepatitis B virus (HBV), hepatitis C virus (HCV) and GB virus-C (GBV-C) infections in 348 Siberian natives who lived in the Kamchatka Peninsula of Russia. Of 348 samples studied, the seroprevalence of HBsAg and anti-HBs were 11·8% (41 of 348 samples) and 35·9% (125 o...

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Veröffentlicht in:Epidemiology and infection 1999-02, Vol.122 (1), p.139-144
Hauptverfasser: OHBA, K., MIZOKAMI, M., KATO, T., UEDA, R., GURTSENVITCH, V., SENYUTA, N., SYRTSEV, A., ZOYA, K., YAMASHITA, M., HAYAMI, M.
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container_end_page 144
container_issue 1
container_start_page 139
container_title Epidemiology and infection
container_volume 122
creator OHBA, K.
MIZOKAMI, M.
KATO, T.
UEDA, R.
GURTSENVITCH, V.
SENYUTA, N.
SYRTSEV, A.
ZOYA, K.
YAMASHITA, M.
HAYAMI, M.
description We studied the seroprevalence of hepatitis B virus (HBV), hepatitis C virus (HCV) and GB virus-C (GBV-C) infections in 348 Siberian natives who lived in the Kamchatka Peninsula of Russia. Of 348 samples studied, the seroprevalence of HBsAg and anti-HBs were 11·8% (41 of 348 samples) and 35·9% (125 of 348 samples), respectively. The prevalence of HCV infection was 1·4% (5 of 348 samples), and that of GBV-C RNA, using RT–PCR methods, was 7·5% (26 of 348 samples). In Siberia, the prevalences of HBV and GBV-C infections were about tenfold higher than those in Japan. The prevalence of HBsAg in subjects under 50 years of age was significantly higher than that in those over 50 years old (P
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Of 348 samples studied, the seroprevalence of HBsAg and anti-HBs were 11·8% (41 of 348 samples) and 35·9% (125 of 348 samples), respectively. The prevalence of HCV infection was 1·4% (5 of 348 samples), and that of GBV-C RNA, using RT–PCR methods, was 7·5% (26 of 348 samples). In Siberia, the prevalences of HBV and GBV-C infections were about tenfold higher than those in Japan. The prevalence of HBsAg in subjects under 50 years of age was significantly higher than that in those over 50 years old (P&lt;0·05). Because HBV infection is highly endemic in Siberia, we propose that the community-based mass immunization must be conducted as soon as possible in this area.</description><identifier>ISSN: 0950-2688</identifier><identifier>EISSN: 1469-4409</identifier><identifier>DOI: 10.1017/S0950268898001940</identifier><identifier>PMID: 10098797</identifier><language>eng</language><publisher>England: Cambridge University Press</publisher><subject>Adolescent ; Adult ; Age Distribution ; Aged ; Aged, 80 and over ; Endemic Diseases - prevention &amp; control ; Endemic Diseases - statistics &amp; numerical data ; Female ; Flaviviridae ; GB virus C ; Genotypes ; Hepacivirus ; Hepatitis antigens ; Hepatitis B - epidemiology ; Hepatitis B - immunology ; Hepatitis B - prevention &amp; control ; Hepatitis B - virology ; Hepatitis B virus ; Hepatitis C - epidemiology ; Hepatitis C - immunology ; Hepatitis C - prevention &amp; control ; Hepatitis C - virology ; Hepatitis C virus ; Hepatitis G virus ; Hepatitis, Viral, Human - epidemiology ; Hepatitis, Viral, Human - immunology ; Hepatitis, Viral, Human - prevention &amp; control ; Hepatitis, Viral, Human - virology ; Humans ; Infections ; Male ; Middle Aged ; Population Surveillance ; Reverse Transcriptase Polymerase Chain Reaction ; RNA ; Seroepidemiologic Studies ; Serotyping ; Siberia - epidemiology ; Vaccination ; Viruses</subject><ispartof>Epidemiology and infection, 1999-02, Vol.122 (1), p.139-144</ispartof><rights>1999 Cambridge University Press</rights><rights>Copyright 1999 Cambridge University Press</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c529t-aedc545d1dbe2a3cb6caffdc22b1907144b155474aba40fe6eb1661b8d92e7223</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/3865246$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/3865246$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,723,776,780,799,881,27901,27902,53766,53768,57992,58225</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10098797$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>OHBA, K.</creatorcontrib><creatorcontrib>MIZOKAMI, M.</creatorcontrib><creatorcontrib>KATO, T.</creatorcontrib><creatorcontrib>UEDA, R.</creatorcontrib><creatorcontrib>GURTSENVITCH, V.</creatorcontrib><creatorcontrib>SENYUTA, N.</creatorcontrib><creatorcontrib>SYRTSEV, A.</creatorcontrib><creatorcontrib>ZOYA, K.</creatorcontrib><creatorcontrib>YAMASHITA, M.</creatorcontrib><creatorcontrib>HAYAMI, M.</creatorcontrib><title>Seroprevalence of hepatitis B virus, hepatitis C virus and GB virus-C infections in Siberia</title><title>Epidemiology and infection</title><addtitle>Epidemiol. Infect</addtitle><description>We studied the seroprevalence of hepatitis B virus (HBV), hepatitis C virus (HCV) and GB virus-C (GBV-C) infections in 348 Siberian natives who lived in the Kamchatka Peninsula of Russia. Of 348 samples studied, the seroprevalence of HBsAg and anti-HBs were 11·8% (41 of 348 samples) and 35·9% (125 of 348 samples), respectively. The prevalence of HCV infection was 1·4% (5 of 348 samples), and that of GBV-C RNA, using RT–PCR methods, was 7·5% (26 of 348 samples). In Siberia, the prevalences of HBV and GBV-C infections were about tenfold higher than those in Japan. The prevalence of HBsAg in subjects under 50 years of age was significantly higher than that in those over 50 years old (P&lt;0·05). Because HBV infection is highly endemic in Siberia, we propose that the community-based mass immunization must be conducted as soon as possible in this area.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Distribution</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Endemic Diseases - prevention &amp; control</subject><subject>Endemic Diseases - statistics &amp; numerical data</subject><subject>Female</subject><subject>Flaviviridae</subject><subject>GB virus C</subject><subject>Genotypes</subject><subject>Hepacivirus</subject><subject>Hepatitis antigens</subject><subject>Hepatitis B - epidemiology</subject><subject>Hepatitis B - immunology</subject><subject>Hepatitis B - prevention &amp; control</subject><subject>Hepatitis B - virology</subject><subject>Hepatitis B virus</subject><subject>Hepatitis C - epidemiology</subject><subject>Hepatitis C - immunology</subject><subject>Hepatitis C - prevention &amp; control</subject><subject>Hepatitis C - virology</subject><subject>Hepatitis C virus</subject><subject>Hepatitis G virus</subject><subject>Hepatitis, Viral, Human - epidemiology</subject><subject>Hepatitis, Viral, Human - immunology</subject><subject>Hepatitis, Viral, Human - prevention &amp; 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MIZOKAMI, M. ; KATO, T. ; UEDA, R. ; GURTSENVITCH, V. ; SENYUTA, N. ; SYRTSEV, A. ; ZOYA, K. ; YAMASHITA, M. ; HAYAMI, M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c529t-aedc545d1dbe2a3cb6caffdc22b1907144b155474aba40fe6eb1661b8d92e7223</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Distribution</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Endemic Diseases - prevention &amp; control</topic><topic>Endemic Diseases - statistics &amp; numerical data</topic><topic>Female</topic><topic>Flaviviridae</topic><topic>GB virus C</topic><topic>Genotypes</topic><topic>Hepacivirus</topic><topic>Hepatitis antigens</topic><topic>Hepatitis B - epidemiology</topic><topic>Hepatitis B - immunology</topic><topic>Hepatitis B - prevention &amp; control</topic><topic>Hepatitis B - virology</topic><topic>Hepatitis B virus</topic><topic>Hepatitis C - epidemiology</topic><topic>Hepatitis C - immunology</topic><topic>Hepatitis C - prevention &amp; control</topic><topic>Hepatitis C - virology</topic><topic>Hepatitis C virus</topic><topic>Hepatitis G virus</topic><topic>Hepatitis, Viral, Human - epidemiology</topic><topic>Hepatitis, Viral, Human - immunology</topic><topic>Hepatitis, Viral, Human - prevention &amp; control</topic><topic>Hepatitis, Viral, Human - virology</topic><topic>Humans</topic><topic>Infections</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Population Surveillance</topic><topic>Reverse Transcriptase Polymerase Chain Reaction</topic><topic>RNA</topic><topic>Seroepidemiologic Studies</topic><topic>Serotyping</topic><topic>Siberia - epidemiology</topic><topic>Vaccination</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>OHBA, K.</creatorcontrib><creatorcontrib>MIZOKAMI, M.</creatorcontrib><creatorcontrib>KATO, T.</creatorcontrib><creatorcontrib>UEDA, R.</creatorcontrib><creatorcontrib>GURTSENVITCH, V.</creatorcontrib><creatorcontrib>SENYUTA, N.</creatorcontrib><creatorcontrib>SYRTSEV, A.</creatorcontrib><creatorcontrib>ZOYA, K.</creatorcontrib><creatorcontrib>YAMASHITA, M.</creatorcontrib><creatorcontrib>HAYAMI, M.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Epidemiology and infection</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>OHBA, K.</au><au>MIZOKAMI, M.</au><au>KATO, T.</au><au>UEDA, R.</au><au>GURTSENVITCH, V.</au><au>SENYUTA, N.</au><au>SYRTSEV, A.</au><au>ZOYA, K.</au><au>YAMASHITA, M.</au><au>HAYAMI, M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Seroprevalence of hepatitis B virus, hepatitis C virus and GB virus-C infections in Siberia</atitle><jtitle>Epidemiology and infection</jtitle><addtitle>Epidemiol. Infect</addtitle><date>1999-02</date><risdate>1999</risdate><volume>122</volume><issue>1</issue><spage>139</spage><epage>144</epage><pages>139-144</pages><issn>0950-2688</issn><eissn>1469-4409</eissn><abstract>We studied the seroprevalence of hepatitis B virus (HBV), hepatitis C virus (HCV) and GB virus-C (GBV-C) infections in 348 Siberian natives who lived in the Kamchatka Peninsula of Russia. Of 348 samples studied, the seroprevalence of HBsAg and anti-HBs were 11·8% (41 of 348 samples) and 35·9% (125 of 348 samples), respectively. The prevalence of HCV infection was 1·4% (5 of 348 samples), and that of GBV-C RNA, using RT–PCR methods, was 7·5% (26 of 348 samples). In Siberia, the prevalences of HBV and GBV-C infections were about tenfold higher than those in Japan. The prevalence of HBsAg in subjects under 50 years of age was significantly higher than that in those over 50 years old (P&lt;0·05). Because HBV infection is highly endemic in Siberia, we propose that the community-based mass immunization must be conducted as soon as possible in this area.</abstract><cop>England</cop><pub>Cambridge University Press</pub><pmid>10098797</pmid><doi>10.1017/S0950268898001940</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
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subjects Adolescent
Adult
Age Distribution
Aged
Aged, 80 and over
Endemic Diseases - prevention & control
Endemic Diseases - statistics & numerical data
Female
Flaviviridae
GB virus C
Genotypes
Hepacivirus
Hepatitis antigens
Hepatitis B - epidemiology
Hepatitis B - immunology
Hepatitis B - prevention & control
Hepatitis B - virology
Hepatitis B virus
Hepatitis C - epidemiology
Hepatitis C - immunology
Hepatitis C - prevention & control
Hepatitis C - virology
Hepatitis C virus
Hepatitis G virus
Hepatitis, Viral, Human - epidemiology
Hepatitis, Viral, Human - immunology
Hepatitis, Viral, Human - prevention & control
Hepatitis, Viral, Human - virology
Humans
Infections
Male
Middle Aged
Population Surveillance
Reverse Transcriptase Polymerase Chain Reaction
RNA
Seroepidemiologic Studies
Serotyping
Siberia - epidemiology
Vaccination
Viruses
title Seroprevalence of hepatitis B virus, hepatitis C virus and GB virus-C infections in Siberia
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