Reactive Oxygen Species Mediate Mitogenic Growth Factor Signaling Pathways in Human Leiomyoma Smooth Muscle Cells

Uterine leiomyomas are benign uterine tumors characterized by extracellular matrix remodeling, increased collagen deposition, and increased smooth muscle cell (SMC) proliferation. The reactive oxygen species (ROS) producing NADPH oxidase complex has been shown to be involved in the signaling pathway...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biology of reproduction 2010-02, Vol.82 (2), p.341-351
Hauptverfasser:	Mesquita, Fernando S, Dyer, Summer N, Heinrich, Daniel A, Bulun, Serdar E, Marsh, Erica E, Nowak, Romana A
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Division - drug effects Cell Line, Tumor DNA - biosynthesis Enzyme Activation - drug effects Enzyme Inhibitors - pharmacology Epidermal Growth Factor - pharmacology Female Fundamental and applied biological sciences. Psychology Humans Hydrogen Peroxide - pharmacology Leiomyoma - metabolism Mitogen-Activated Protein Kinases - metabolism Muscle, Smooth - metabolism NADPH Oxidases - antagonists & inhibitors Platelet-Derived Growth Factor - pharmacology Reactive Oxygen Species - antagonists & inhibitors Reactive Oxygen Species - metabolism Reactive Oxygen Species - pharmacology Signal Transduction - physiology Uterine Neoplasms - metabolism Vertebrates: reproduction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!