Transport of prion protein across the blood–brain barrier

The cellular form of the prion protein (PrP c) is necessary for the development of prion diseases and is a highly conserved protein that may play a role in neuroprotection. PrP c is found in both blood and cerebrospinal fluid and is likely produced by both peripheral tissues and the central nervous...

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Veröffentlicht in:	Experimental neurology 2009-07, Vol.218 (1), p.162-167
Hauptverfasser:	Banks, W.A., Robinson, Sandra M., Diaz-Espinoza, R., Urayama, A., Soto, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood-Brain Barrier - physiology Blood–brain barrier Capillary Permeability Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Fundamental and applied biological sciences. Psychology Iodine Isotopes - pharmacokinetics Male Medical sciences Mice Neurology Peptide Prion Prions - metabolism Prions - pharmacokinetics Protein Transport - physiology Scrapie Time Factors Tissue Distribution Transport Vertebrates: nervous system and sense organs
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