Donor-recipient mismatch for common gene deletion polymorphisms in graft-versus-host disease

Transplantation and pregnancy, in which two diploid genomes reside in one body, can each lead to diseases in which immune cells from one individual target antigens encoded in the other's genome. One such disease, graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation (HS...

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Veröffentlicht in:	Nature genetics 2009-12, Vol.41 (12), p.1341-1344
Hauptverfasser:	McCarroll, Steven A, Bradner, James E, Turpeinen, Hannu, Volin, Liisa, Martin, Paul J, Chilewski, Shannon D, Antin, Joseph H, Lee, Stephanie J, Ruutu, Tapani, Storer, Barry, Warren, Edus H, Zhang, Bo, Zhao, Lue Ping, Ginsburg, David, Soiffer, Robert J, Partanen, Jukka, Hansen, John A, Ritz, Jerome, Palotie, Aarno, Altshuler, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Agriculture Amino acids Animal Genetics and Genomics Biological and medical sciences Biomedical and Life Sciences Biomedicine Bone marrow Bone Marrow Transplantation Cancer Cancer Research Cohort Studies Complications and side effects Female Fundamental and applied biological sciences. Psychology Gene Deletion Gene Function Gene mutations Genes Genetic aspects Genetics Genetics of eukaryotes. Biological and molecular evolution Genome, Human Genotype & phenotype Glucuronosyltransferase - genetics Graft versus host reaction Graft vs Host Disease - genetics Graft vs Host Disease - immunology Health aspects Hematopoietic Stem Cell Transplantation Hematopoietic stem cells HLA Antigens - genetics Hospitals Human Genetics Humans Immune system letter Life sciences Lymphocytes Male Medical research Minor Histocompatibility Antigens Patients Polymorphism, Genetic Risk factors Stem cells Transplantation Transplants & implants
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