PB1 Domain Interaction of p62/Sequestosome 1 and MEKK3 Regulates NF-κB Activation

p62/Sequestosome 1 is a scaffold protein involved in the regulation of autophagy, trafficking of proteins to the proteasome, and activation of NF-κB. p62 encodes an N-terminal PB1 domain in addition to the ZZ domain, TRAF6-binding domain, LC3 interaction region, and ubiquitin-associated domain, each...

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Veröffentlicht in:	The Journal of biological chemistry 2010-01, Vol.285 (3), p.2077-2089
Hauptverfasser:	Nakamura, Kazuhiro, Kimple, Adam J., Siderovski, David P., Johnson, Gary L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Mechanisms of Signal Transduction MEKK3 NF-κB p62 PB1 Domain Sequestosome 1 Speckles TRAF6
Online-Zugang:	Volltext
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