Interleukin-25 Expressed by Brain Capillary Endothelial Cells Maintains Blood-Brain Barrier Function in a Protein Kinase Cϵ-dependent Manner

Interleukin (IL)-25, a member of the IL-17 family of cytokines, is expressed in the brains of normal mice. However, the cellular source of IL-25 and its function in the brain remain to be elucidated. Here, we show that IL-25 plays an important role in preventing infiltration of the inflammatory cell...

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Veröffentlicht in:The Journal of biological chemistry 2009-11, Vol.284 (46), p.31834-31842
Hauptverfasser: Sonobe, Yoshifumi, Takeuchi, Hideyuki, Kataoka, Kunio, Li, Hua, Jin, Shijie, Mimuro, Maya, Hashizume, Yoshio, Sano, Yasuteru, Kanda, Takashi, Mizuno, Tetsuya, Suzumura, Akio
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Sprache:eng
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