Genome-wide association studies of rheumatoid arthritis data via multiple hypothesis testing methods for correlated tests

Genome-wide association studies often involve testing hundreds of thousands of single-nucleotide polymorphisms (SNPs). These tests may be highly correlated because of linkage disequilibrium among SNPs. Multiple testing correction ignoring the correlation among markers, as is done in the Bonferroni p...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	BMC proceedings 2009-12, Vol.3 Suppl 7 (Suppl 7), p.S38-S38, Article S38
Hauptverfasser:	Kang, Guolian, Childers, Douglas K, Liu, Nianjun, Zhang, Kui, Gao, Guimin
Format:	Artikel
Sprache:	eng
Schlagworte:	Generalized linear models Genomes Hypothesis testing Methods Proceedings Random variables Statistics Studies
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!