Prognostic impact of proliferative index determined by quantitative image analysis and the International Prognostic Index in patients with mantle cell lymphoma

Background: The proliferative index (PI) is a powerful prognostic factor in mantle cell lymphoma (MCL); however, its utility is hampered by interobserver variability. The mantle cell international prognostic index (MIPI) has been reported to have prognostic importance. In this study, we determined t...

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Veröffentlicht in:	Annals of oncology 2010, Vol.21 (1), p.133-139
Hauptverfasser:	Schaffel, R., Hedvat, C. V., Teruya-Feldstein, J., Persky, D., Maragulia, J., Lin, D., Portlock, C. S., Moskowitz, C. H., Zelenetz, A. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Biomarkers, Tumor - analysis Cell Proliferation - drug effects Disease-Free Survival Female Hematologic and hematopoietic diseases Humans Image Processing, Computer-Assisted - methods Immunohistochemistry Kaplan-Meier Estimate Ki-67 Antigen - analysis Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, Mantle-Cell - drug therapy Lymphoma, Mantle-Cell - mortality Lymphoma, Mantle-Cell - pathology Male mantle cell lymphoma Medical sciences Middle Aged Original Pharmacology. Drug treatments Prognosis proliferative index quantitative image analysis
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