Tracing the Origin of Glomerular Extracapillary Lesions from Parietal Epithelial Cells

Cellular lesions form in Bowman's space in both crescentic glomerulonephritis and collapsing glomerulopathy. The pathomechanism and origin of the proliferating cells in these lesions are unknown. In this study, we examined proliferating cells by lineage tracing of either podocytes or parietal e...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2009-12, Vol.20 (12), p.2604-2615
Hauptverfasser:	SMEETS, Bart, UHLIG, Sandra, FUSS, Astrid, MOOREN, Fieke, WETZELS, Jack F. M, FLOEGE, Jürgen, MOELLER, Marcus J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basic Research Biological and medical sciences Bowman Capsule - metabolism Bowman Capsule - pathology Cell Proliferation Claudin-1 Disease Models, Animal Epithelial Cells - metabolism Epithelial Cells - pathology Glomerulonephritis - metabolism Glomerulonephritis - pathology Hyaluronan Receptors - metabolism Hyperplasia Kidney Glomerulus - metabolism Kidney Glomerulus - pathology Medical sciences Membrane Proteins - metabolism Mice Mice, Transgenic Nephrology. Urinary tract diseases Podocytes - metabolism Podocytes - pathology
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