Epstein–Barr virus infection is not a characteristic feature of multiple sclerosis brain

Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system (CNS) that is thought to be caused by a combination of genetic and environmental factors. To date, considerable evidence has associated Epstein–Barr virus (EBV) infection with disease development. However, it r...

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Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 2009-12, Vol.132 (12), p.3318-3328
Hauptverfasser:	Willis, Simon N., Stadelmann, Christine, Rodig, Scott J., Caron, Tyler, Gattenloehner, Stefan, Mallozzi, Scott S., Roughan, Jill E., Almendinger, Stefany E., Blewett, Megan M., Brück, Wolfgang, Hafler, David A., O’Connor, Kevin C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult B cells B-Lymphocytes - immunology B-Lymphocytes - virology Biological and medical sciences Brain - pathology Brain - virology Causality Child Cohort Studies Epstein-Barr virus Epstein-Barr Virus Infections - complications Epstein-Barr Virus Infections - pathology Epstein-Barr Virus Infections - physiopathology Herpesvirus 4, Human - genetics Herpesvirus 4, Human - immunology Humans Immunity, Humoral - physiology Jurkat Cells Lymphocyte Activation - immunology Medical sciences Multiple Sclerosis - pathology Multiple Sclerosis - physiopathology Multiple Sclerosis - virology Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis multiple sclerosis brain Neurology Original Polymerase Chain Reaction - methods RNA, Viral - analysis RNA, Viral - genetics RNA, Viral - metabolism
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