Recent developments in low molecular weight complement inhibitors

As a key part of the innate immune system, complement plays an important role not only in defending against invading pathogens but also in many other biological processes. Inappropriate or excessive activation of complement has been linked to many autoimmune, inflammatory, and neurodegenerative dise...

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Veröffentlicht in:	Molecular immunology 2009-12, Vol.47 (2-3), p.185-195
Hauptverfasser:	Qu, Hongchang, Ricklin, Daniel, Lambris, John D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals C3aR antagonist C5aR antagonist Complement Inactivator Proteins - immunology Complement inhibitors Complement System Proteins - immunology Compstatin Humans Models, Molecular PMX205 PMX53 Protein Binding - immunology Receptors, Complement - immunology SB290157 Serine Proteases - immunology
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