Activation of early signaling transcription factor, NF-κB following low-level manganese exposure

Occupational and environmental exposure to manganese (Mn 2+) is an increasing problem. It manifests neuronal degeneration characterized by dyskinesia resembling Parkinson's disease. The study was performed to test the hypotheses whether exposure to Mn 2+ alters cellular physiology and promotes...

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Veröffentlicht in:	Toxicology letters 2002-12, Vol.136 (2), p.151-158
Hauptverfasser:	Ramesh, Govindarajan T, Ghosh, Debabrata, Gunasekar, Palur G
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases Medical sciences Metals and various inorganic compounds Mn 2 Neurotoxicity NF-κB Oxidative stress PC12 cells Toxicology
Online-Zugang:	Volltext
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