Prolactin induces Egr-1 gene expression in cultured hypothalamic cells and in the rat hypothalamus

Abstract Prolactin (PRL), the major lactogenic hormone, acts also as neuromodulator and regulator of neuronal and glial plasticity in the brain. There is an increase in synthesis and release of PRL within the hypothalamus during peripartum and in response to stress. To identify mechanisms by which P...

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Veröffentlicht in:	Brain research 2009-11, Vol.1302, p.34-41
Hauptverfasser:	Blume, Annegret, Torner, Luz, Liu, Ying, Subburaju, Sivan, Aguilera, Greti, Neumann, Inga D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cells, Cultured Corticotropin-Releasing Hormone - metabolism Early Growth Response Protein 1 - drug effects Early Growth Response Protein 1 - genetics Early Growth Response Protein 1 - metabolism Enzyme Inhibitors - pharmacology Female Fundamental and applied biological sciences. Psychology Gene Expression - drug effects Gene Expression - genetics Hormones and neuropeptides. Regulation Hypothalamo-pituitary-adrenal axis Hypothalamus - cytology Hypothalamus - drug effects Hypothalamus - metabolism Hypothalamus. Hypophysis. Epiphysis. Urophysis Immunohistochemistry Lactation MAP Kinase Signaling System - drug effects MAP Kinase Signaling System - physiology Neurology Neuronal Plasticity - drug effects Neuronal Plasticity - genetics Neurons - drug effects Neurons - metabolism Neurons - secretion Neuroplasticity Oxytocin - drug effects Oxytocin - metabolism Oxytocin - secretion Paraventricular Hypothalamic Nucleus - cytology Paraventricular Hypothalamic Nucleus - drug effects Paraventricular Hypothalamic Nucleus - metabolism Prolactin - metabolism Prolactin - pharmacology Rats Rats, Wistar RNA, Messenger - drug effects RNA, Messenger - metabolism Signaling Stress Supraoptic Nucleus - cytology Supraoptic Nucleus - drug effects Supraoptic Nucleus - metabolism Transcription factor Vertebrates: endocrinology
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