Efficiently finding genome-wide three-way gene interactions from transcript- and genotype-data

Motivation: We address the issue of finding a three-way gene interaction, i.e. two interacting genes in expression under the genotypes of another gene, given a dataset in which expressions and genotypes are measured at once for each individual. This issue can be a general, switching mechanism in exp...

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Veröffentlicht in:	Bioinformatics 2009-11, Vol.25 (21), p.2735-2743
Hauptverfasser:	Kayano, Mitsunori, Takigawa, Ichigaku, Shiga, Motoki, Tsuda, Koji, Mamitsuka, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Databases, Genetic Fundamental and applied biological sciences. Psychology Gene Expression Gene Expression Profiling - methods General aspects Genome Genomics - methods Genotype Logistic Models Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Original Papers Software
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