The heritability and genetics of frontotemporal lobar degeneration

Frontotemporal lobar degeneration (FTLD) is a genetically and pathologically heterogeneous neurodegenerative disorder. We collected blood samples from a cohort of 225 patients with a diagnosis within the FTLD spectrum and examined the heritability of FTLD by giving each patient a family history scor...

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Veröffentlicht in:	Neurology 2009-11, Vol.73 (18), p.1451-1456
Hauptverfasser:	ROHRER, J. D, GUERREIRO, R, MACKENZIE, I. R. A, WARREN, J. D, DE SILVA, R, HOLTON, J, REVESZ, T, HARDY, J, MEAD, S, ROSSOR, M. N, VANDROVCOVA, J, UPHILL, J, REIMAN, D, BECK, J, ISAACS, A. M, AUTHIER, A, FERRARI, R, FOX, N. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - genetics Aged Aged, 80 and over Biological and medical sciences Cell Cycle Proteins - genetics Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dementia - genetics Dementia - pathology DNA-Binding Proteins - genetics Endosomal Sorting Complexes Required for Transport Female Genetic Predisposition to Disease Humans Intercellular Signaling Peptides and Proteins - genetics Male Medical sciences Motor Neuron Disease - genetics Mutation Nerve Tissue Proteins - genetics Neurology Neuropsychological Tests RNA-Binding Protein FUS - genetics Surveys and Questionnaires tau Proteins - genetics Valosin Containing Protein
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