On the mechanism underlying the divergent retinal and bristle defects of M8 (E(spl)D) in Drosophila

Our results, using endogenous mutants and Gal4‐UAS driven transgenes, implicate multisite phosphorylation in repression by E(spl)M8. We propose that these phosphorylations occur in the morphogenetic furrow (MF) to reverse an auto‐inhibited state of M8, enabling repression of Atonal during R8 specifi...

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Veröffentlicht in:	Genesis (New York, N.Y. : 2000) N.Y. : 2000), 2009-07, Vol.47 (7), p.456-468
Hauptverfasser:	Kahali, Bhaskar, Bose, Anasua, Karandikar, Umesh, Bishop, Clifton P., Bidwai, Ashok P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CK2 Drosophila Drosophila - embryology Drosophila - genetics Drosophila Proteins - physiology E(spl)D lateral inhibition Neurogenesis Phosphorylation Retina - embryology Signal Transduction Two-Hybrid System Techniques
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