Quantification of Spatial Parameters in 3D Cellular Constructs Using Graph Theory

Multispectral three-dimensional (3D) imaging provides spatial information for biological structures that cannot be measured by traditional methods. This work presents a method of tracking 3D biological structures to quantify changes over time using graph theory. Cell-graphs were generated based on t...

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Veröffentlicht in:	BioMed research international 2009-01, Vol.2009 (2009), p.1-16
Hauptverfasser:	Lund, A. W., Bilgin, C. C., Hasan, M. A., McKeen, L. M., Stegemann, J. P., Yener, Bülent, Zaki, M. J., Plopper, George E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomedical research Cell Count Cell Culture Techniques - methods Cell nuclei Collagen Type I - pharmacology Computer science Computerized, statistical medical data processing and models in biomedicine Fluorescence Graph theory Graphs Humans Hydrogel, Polyethylene Glycol Dimethacrylate - pharmacology Imaging, Three-Dimensional - methods Medical sciences Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - drug effects Microscopy, Confocal Models and simulation Models, Biological Neural networks Pharmacology. Drug treatments Properties Time Factors Tissue engineering
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