Perineural Invasion Is an Independent Predictor of Outcome in Colorectal Cancer

Perineural invasion (PNI) is associated with decreased survival in several malignancies, but its significance in colorectal cancer (CRC) remains to be clearly defined. We evaluated PNI as a potential prognostic indicator in CRC, focusing on its significance in node-negative patients. We identified 2...

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Veröffentlicht in:	Journal of clinical oncology 2009-11, Vol.27 (31), p.5131-5137
Hauptverfasser:	Liebig, Catherine, Ayala, Gustavo, Wilks, Jonathan, Verstovsek, Gordana, Liu, Hao, Agarwal, Neeti, Berger, David H, Albo, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - mortality Adenocarcinoma - pathology Adult Aged Aged, 80 and over Antineoplastic Agents - therapeutic use Biological and medical sciences Chemotherapy, Adjuvant Colorectal Neoplasms - mortality Colorectal Neoplasms - pathology Colorectal Neoplasms - therapy Combined Modality Therapy Digestive System Surgical Procedures Disease-Free Survival Female Gastroenterology. Liver. Pancreas. Abdomen Humans Kaplan-Meier Estimate Male Medical sciences Middle Aged Neoadjuvant Therapy Neoplasm Invasiveness - pathology Neoplasm Staging Original Reports Peripheral Nerves - pathology Prognosis Radiotherapy Radiotherapy, Adjuvant Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Treatment Outcome Tumors
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