Elevated immune response in the brain of autistic patients

Abstract This study determined immune activities in the brain of ASD patients and matched normal subjects by examining cytokines in the brain tissue. Our results showed that proinflammatory cytokines (TNF-α, IL-6 and GM-CSF), Th1 cytokine (IFN-γ) and chemokine (IL-8) were significantly increased in...

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Veröffentlicht in:	Journal of neuroimmunology 2009-02, Vol.207 (1), p.111-116
Hauptverfasser:	Li, Xiaohong, Chauhan, Abha, Sheikh, Ashfaq M, Patil, Sangita, Chauhan, Ved, Li, Xiu-Min, Ji, Lina, Brown, Ted, Malik, Mazhar
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Allergy and Immunology Autistic Disorder - immunology Autistic Disorder - pathology Autistic spectrum disorders (ASD) Brain - immunology Brain - pathology Case-Control Studies Chemokines - metabolism Child Child, Preschool Cytokines Cytokines - metabolism Female Flow cytometry method Humans Immune response Inflammation Male Multiplexed bead analysis Neurology Statistics, Nonparametric Th1 Cells - immunology Th2 Cells - immunology Young Adult
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