The Ess1 prolyl isomerase is required for transcription termination of small non-coding RNAs via the Nrd1 pathway

Genome-wide studies have identified abundant small, non-coding RNAs including snRNAs, snoRNAs, cryptic unstable transcripts (CUTs), and upstream regulatory RNAs (uRNAs) that are transcribed by RNA polymerase II (pol II) and terminated by a Nrd1-dependent pathway. Here, we show that the prolyl isomer...

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Veröffentlicht in:Molecular cell 2009-10, Vol.36 (2), p.255-266
Hauptverfasser: Singh, Navjot, Ma, Zhuo, Gemmill, Trent, Wu, Xiaoyun, DeFiglio, Holland, Rossettini, Anne, Rabeler, Christina, Beane, Olivia, Morse, Randall, Palumbo, Michael J., Hanes, Steven D.
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Sprache:eng
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