Gastric choriocarcinoma admixed with an α-fetoprotein-producing adenocarcinoma and separated adenocarcinoma
We report a case of gastric choriocarcinoma admixed with an α-fetoprotein (AFP)-producing adeno-carcinoma. A 70-year-old man was hospitalized for gastric cancer that was detected during screening by esophagogastroduodenoscopy (EGD). Initial laboratory data showed the increased serum level of AFP and...
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Veröffentlicht in: | World journal of gastroenterology : WJG 2009-10, Vol.15 (40), p.5106-5108 |
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description | We report a case of gastric choriocarcinoma admixed with an α-fetoprotein (AFP)-producing adeno-carcinoma. A 70-year-old man was hospitalized for gastric cancer that was detected during screening by esophagogastroduodenoscopy (EGD). Initial laboratory data showed the increased serum level of AFP and EGD revealed a 5-cm ulcerofungating mass in the greater curvature of the gastric antrum. The patient underwent radical subtotal gastrectomywith D2 lymph node dissection and Billroth gastrojejunostomy. Histopathological evaluation confirmed double primary gastric cancer: gastric choriocarcinoma admixed with an AFP-producing adenocarcinoma and separated adenocarcinoma. At 2 wk postoperatively, his human chorionic gonadotropin and AFP levels had reduced and six cycles of adjuvant chemotherapy were initiated. No recurrence or distant metastasis was observed at 4 years postoperatively. |
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A 70-year-old man was hospitalized for gastric cancer that was detected during screening by esophagogastroduodenoscopy (EGD). Initial laboratory data showed the increased serum level of AFP and EGD revealed a 5-cm ulcerofungating mass in the greater curvature of the gastric antrum. The patient underwent radical subtotal gastrectomywith D2 lymph node dissection and Billroth gastrojejunostomy. Histopathological evaluation confirmed double primary gastric cancer: gastric choriocarcinoma admixed with an AFP-producing adenocarcinoma and separated adenocarcinoma. At 2 wk postoperatively, his human chorionic gonadotropin and AFP levels had reduced and six cycles of adjuvant chemotherapy were initiated. No recurrence or distant metastasis was observed at 4 years postoperatively.</description><identifier>ISSN: 1007-9327</identifier><identifier>EISSN: 2219-2840</identifier><identifier>DOI: 10.3748/wjg.15.5106</identifier><identifier>PMID: 19860007</identifier><language>eng</language><publisher>United States: Center for Gastric Cancer, National Cancer Center,111 Jeongbalsanro, Ilsandong-Gu, Goyang-Si, Gyeonggi-Do 410-769, South Korea</publisher><subject>Adenocarcinoma - drug therapy ; Aged ; alpha-Fetoproteins - biosynthesis ; Case Report ; Choriocarcinoma - diagnosis ; Choriocarcinoma - pathology ; Chorionic Gonadotropin - metabolism ; Gastrectomy ; Humans ; Lymph Nodes - pathology ; Male ; Prognosis ; Stomach Neoplasms - diagnosis ; Stomach Neoplasms - pathology ; Treatment Outcome ; 人绒毛膜促性腺激素 ; 甲胎蛋白 ; 蛋白水平</subject><ispartof>World journal of gastroenterology : WJG, 2009-10, Vol.15 (40), p.5106-5108</ispartof><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><rights>2009 The WJG Press and Baishideng. All rights reserved. 2009</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c436t-6f598121653883684957a18767eba3bde894979c4ead0731d1ae66d034cfcfad3</citedby><cites>FETCH-LOGICAL-c436t-6f598121653883684957a18767eba3bde894979c4ead0731d1ae66d034cfcfad3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/84123X/84123X.jpg</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768893/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768893/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19860007$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Eom, Bang Wool</creatorcontrib><creatorcontrib>Jung, So-Youn</creatorcontrib><creatorcontrib>Yoon, Hongman</creatorcontrib><creatorcontrib>Kook, Myeong-Cherl</creatorcontrib><creatorcontrib>Ryu, Keun-Won</creatorcontrib><creatorcontrib>Lee, Jun-Ho</creatorcontrib><creatorcontrib>Kim, Young-Woo</creatorcontrib><title>Gastric choriocarcinoma admixed with an α-fetoprotein-producing adenocarcinoma and separated adenocarcinoma</title><title>World journal of gastroenterology : WJG</title><addtitle>World Journal of Gastroenterology</addtitle><description>We report a case of gastric choriocarcinoma admixed with an α-fetoprotein (AFP)-producing adeno-carcinoma. A 70-year-old man was hospitalized for gastric cancer that was detected during screening by esophagogastroduodenoscopy (EGD). Initial laboratory data showed the increased serum level of AFP and EGD revealed a 5-cm ulcerofungating mass in the greater curvature of the gastric antrum. The patient underwent radical subtotal gastrectomywith D2 lymph node dissection and Billroth gastrojejunostomy. Histopathological evaluation confirmed double primary gastric cancer: gastric choriocarcinoma admixed with an AFP-producing adenocarcinoma and separated adenocarcinoma. At 2 wk postoperatively, his human chorionic gonadotropin and AFP levels had reduced and six cycles of adjuvant chemotherapy were initiated. No recurrence or distant metastasis was observed at 4 years postoperatively.</description><subject>Adenocarcinoma - drug therapy</subject><subject>Aged</subject><subject>alpha-Fetoproteins - biosynthesis</subject><subject>Case Report</subject><subject>Choriocarcinoma - diagnosis</subject><subject>Choriocarcinoma - pathology</subject><subject>Chorionic Gonadotropin - metabolism</subject><subject>Gastrectomy</subject><subject>Humans</subject><subject>Lymph Nodes - pathology</subject><subject>Male</subject><subject>Prognosis</subject><subject>Stomach Neoplasms - diagnosis</subject><subject>Stomach Neoplasms - pathology</subject><subject>Treatment Outcome</subject><subject>人绒毛膜促性腺激素</subject><subject>甲胎蛋白</subject><subject>蛋白水平</subject><issn>1007-9327</issn><issn>2219-2840</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVks2KFDEUhYMoTju6ci-FCC6k2vxVfjaCDDoKA250HW4nqeq0VUlPUmXrY_kiPpNputGZ1V2c754c7glCzwleM8nV28NuWJNu3REsHqAVpUS3VHH8EK0IxrLVjMoL9KSUHcaUsY4-RhdEK4GruELjNZQ5B9vYbcohWcg2xDRBA24KP71rDmHeNhCbP7_b3s9pn9PsQ2zrdEtFhwr6eHcvuqb4PWSY6_Z98Sl61MNY_LPzvETfPn74evWpvfly_fnq_U1rORNzK_pOK0KJ6JhSTCiuOwlESSH9BtjGeaW5ltpyDw5LRhwBL4TDjNve9uDYJXp38t0vm8k76-OcYTT7HCbIv0yCYO4rMWzNkH4YKoVSmlWDVyeDA8Qe4mB2acmxRjb12BRjzTEmqmKvz-_kdLv4MpspFOvHEaJPSzGScYIZJrqSb06kzamU7Pt_YQg2xxaPxoZ05thipV_czf-fPddWgZdnu22Kw22twWzAfu_D6A2rH6Ber2N_AZltpwQ</recordid><startdate>20091028</startdate><enddate>20091028</enddate><creator>Eom, Bang Wool</creator><creator>Jung, So-Youn</creator><creator>Yoon, Hongman</creator><creator>Kook, Myeong-Cherl</creator><creator>Ryu, Keun-Won</creator><creator>Lee, Jun-Ho</creator><creator>Kim, Young-Woo</creator><general>Center for Gastric Cancer, National Cancer Center,111 Jeongbalsanro, Ilsandong-Gu, Goyang-Si, Gyeonggi-Do 410-769, South Korea</general><general>The WJG Press and Baishideng</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W95</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope><scope>5PM</scope></search><sort><creationdate>20091028</creationdate><title>Gastric choriocarcinoma admixed with an α-fetoprotein-producing adenocarcinoma and separated adenocarcinoma</title><author>Eom, Bang Wool ; 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A 70-year-old man was hospitalized for gastric cancer that was detected during screening by esophagogastroduodenoscopy (EGD). Initial laboratory data showed the increased serum level of AFP and EGD revealed a 5-cm ulcerofungating mass in the greater curvature of the gastric antrum. The patient underwent radical subtotal gastrectomywith D2 lymph node dissection and Billroth gastrojejunostomy. Histopathological evaluation confirmed double primary gastric cancer: gastric choriocarcinoma admixed with an AFP-producing adenocarcinoma and separated adenocarcinoma. At 2 wk postoperatively, his human chorionic gonadotropin and AFP levels had reduced and six cycles of adjuvant chemotherapy were initiated. No recurrence or distant metastasis was observed at 4 years postoperatively.</abstract><cop>United States</cop><pub>Center for Gastric Cancer, National Cancer Center,111 Jeongbalsanro, Ilsandong-Gu, Goyang-Si, Gyeonggi-Do 410-769, South Korea</pub><pmid>19860007</pmid><doi>10.3748/wjg.15.5106</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Baishideng "World Journal of" online journals; PMC (PubMed Central); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
subjects | Adenocarcinoma - drug therapy Aged alpha-Fetoproteins - biosynthesis Case Report Choriocarcinoma - diagnosis Choriocarcinoma - pathology Chorionic Gonadotropin - metabolism Gastrectomy Humans Lymph Nodes - pathology Male Prognosis Stomach Neoplasms - diagnosis Stomach Neoplasms - pathology Treatment Outcome 人绒毛膜促性腺激素 甲胎蛋白 蛋白水平 |
title | Gastric choriocarcinoma admixed with an α-fetoprotein-producing adenocarcinoma and separated adenocarcinoma |
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