The actin-bundling protein fascin is overexpressed in colorectal adenomas and promotes motility in adenoma cells in vitro

Background: Fascin is overexpressed in many cancers, including colorectal, but its role in the malignant transformation of benign colorectal adenomas is unclear. Methods: Immunohistochemical analysis of fascin expression was carried out in resected human colorectal adenoma specimens. The effects of...

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Veröffentlicht in:British journal of cancer 2009-10, Vol.101 (7), p.1124-1129
Hauptverfasser: Qualtrough, D, Singh, K, Banu, N, Paraskeva, C, Pignatelli, M
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Sprache:eng
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