Construction of novel spiroisoxazolines via intramolecular cyclization/methylation

Improved yields for the syntheses of a variety of spiroisoxazolines were achieved through intramolecular cyclization/methylation reactions of functionalized 5,5-disubstituted isoxazolines in one reaction vessel. Aromatic ring containing nitrile oxides and disubstituted geminal alkenes reacted in a 1...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Tetrahedron letters 2009-09, Vol.50 (39), p.5516-5519
Hauptverfasser:	Ellis, Erick D., Xu, Jianping, Valente, Edward J., Hamme, Ashton T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cycloaddition Heterocycles Intramolecular cyclization Regioselectivity Spirocycles
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!