Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury

Astrocytes, one of the predominant types of glial cells, function as both supportive and metabolic cells for the brain. Under cerebral ischemia/reperfusion-induced oxidative conditions, astrocytes accumulate and activate in the ischemic region. DJ-1 has recently been shown to be a sensor of oxidativ...

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Veröffentlicht in:Oxidative medicine and cellular longevity 2009-01, Vol.2 (1), p.36-42
Hauptverfasser: Yanagida, Takashi, Tsushima, Jun, Kitamura, Yoshihisa, Yanagisawa, Daijiro, Takata, Kazuyuki, Shibaike, Tomonori, Yamamoto, Atsuko, Taniguchi, Takashi, Yasui, Hiroyuki, Taira, Takahiro, Morikawa, Shigehiro, Inubushi, Toshihiro, Tooyama, Ikuo, Ariga, Hiroyoshi
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Sprache:eng
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