Oncogenesis caused by loss of the SNF5 tumor suppressor is dependent upon activity of BRG1, the ATPase of the SWI/SNF chromatin remodeling complex

Alterations in chromatin play an important role in oncogenic transformation although the underlying mechanisms are often poorly understood. The SWI/SNF complex contributes to epigenetic regulation by utilizing the energy of ATP hydrolysis to remodel chromatin and thus regulate transcription of targe...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2009-09, Vol.69 (20), p.8094-8101
Hauptverfasser:	Wang, Xi, Sansam, Courtney G., Thom, Christopher S., Metzger, Daniel, Evans, Julia A., Nguyen, Phuong T. L., Roberts, Charles W. M.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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