Organization of Hyaluronan and Versican in the Extracellular Matrix of Human Fibroblasts Treated With the Viral Mimetic Poly I:C

We have examined structural details of hyaluronan- and versican-rich peri-cellular matrices in human lung fibroblasts, as well as fixation effects after treatment with the viral mimetic, poly I:C. Lateral aggregation of hyaluronan chains was promoted by acid-ethanol-formalin fixation compared with a...

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Veröffentlicht in:	The journal of histochemistry and cytochemistry 2009-11, Vol.57 (11), p.1041-1060
Hauptverfasser:	Evanko, Stephen P, Potter-Perigo, Susan, Johnson, Pamela Y, Wight, Thomas N
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Biological Transport - drug effects Cell Movement - drug effects Cell Surface Extensions - drug effects Cell Surface Extensions - metabolism Extracellular Matrix - drug effects Extracellular Matrix - metabolism Fibroblasts - cytology Fibroblasts - drug effects Fibroblasts - metabolism Fibroblasts - ultrastructure Humans Hyaluronic Acid - metabolism Microscopy, Electron, Scanning Monocytes - drug effects Monocytes - metabolism Poly I-C - pharmacology Stress Fibers - drug effects Stress Fibers - metabolism Versicans - metabolism Viruses
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