Interactions of tumor cells with dendritic cells: balancing immunity and tolerance

Dendritic cells (DCs) are antigen-presenting cells specialized to initiate and maintain immunity and tolerance. DCs initiate immune responses in a manner that depends on signals they receive from pathogens, surrounding cells and their products. Most tumors are infiltrated by DCs. Thus, interactions...

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Veröffentlicht in:	Cell death and differentiation 2008-01, Vol.15 (1), p.39-50
Hauptverfasser:	Dhodapkar, M V, Dhodapkar, K M, Palucka, A K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens Apoptosis Biochemistry Biomedical and Life Sciences Cell Biology Cell Cycle Analysis Cell Death Cytokines Cytokines - immunology Cytokines - metabolism Dendritic cells Dendritic Cells - immunology Dendritic Cells - physiology Humans Immune system Immune Tolerance Immunity, Cellular Immunology Immunotherapy Life Sciences Lymphatic system Lymphocytes Neoplasms - immunology Neoplasms - pathology Neoplasms - physiopathology Neoplasms - therapy Pathogens Proteins Receptors, Cell Surface - immunology Receptors, Cell Surface - metabolism review Signal Transduction Stem Cells T-Lymphocytes, Regulatory - immunology Toll-Like Receptors - immunology Toll-Like Receptors - metabolism Tumor necrosis factor-TNF Tumors
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