Bilateral cervical contusion spinal cord injury in rats

There is increasing motivation to develop clinically relevant experimental models for cervical SCI in rodents and techniques to assess deficits in forelimb function. Here we describe a bilateral cervical contusion model in rats. Female Sprague–Dawley rats received mild or moderate cervical contusion...

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Veröffentlicht in:	Experimental neurology 2009-11, Vol.220 (1), p.9-22
Hauptverfasser:	Anderson, Kim D., Sharp, Kelli G., Steward, Oswald
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axotomy - methods Biological and medical sciences Biotin - analogs & derivatives Cervical injury Cervical Vertebrae Contusion Corticospinal tract Dextrans Digital flexors Disease Models, Animal Female Forelimb Forelimb - innervation Forelimb - physiopathology Functional Laterality - physiology Grip strength Growth Cones - physiology Growth Cones - ultrastructure Hand Strength - physiology Injuries of the nervous system and the skull. Diseases due to physical agents Lameness, Animal - etiology Lameness, Animal - pathology Lameness, Animal - physiopathology Medical sciences Movement Disorders - etiology Movement Disorders - pathology Movement Disorders - physiopathology Muscle Strength Dynamometer Nerve Regeneration - physiology Neurologic Examination Neurology Neuronal Plasticity - physiology Physical Stimulation Pyramidal Tracts - injuries Pyramidal Tracts - pathology Pyramidal Tracts - physiopathology Rats Rats, Sprague-Dawley Recovery of Function - physiology Sensation Disorders - etiology Sensation Disorders - pathology Sensation Disorders - physiopathology Spinal Cord Injuries - complications Spinal Cord Injuries - pathology Spinal Cord Injuries - physiopathology Staining and Labeling Traumas. Diseases due to physical agents
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