Subcellular distribution and targeting of the intracellular chloride channel p64

p64 is an intracellular chloride channel originally identified in bovine kidney microsomes. Using a combination of immunofluorescent and electron microscopic technique, we demonstrate that p64 resides in the limiting membranes of perinuclear dense core vesicles which appear to be regulated secretory...

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Veröffentlicht in:	Molecular biology of the cell 1997-04, Vol.8 (4), p.691-704
Hauptverfasser:	Redhead, C, Sullivan, S K, Koseki, C, Fujiwara, K, Edwards, J C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites Biological Transport Cattle Cell Compartmentation Cell Membrane - drug effects Cell Membrane - metabolism Chloride Channels - chemistry Chloride Channels - genetics Chloride Channels - metabolism Fluorescent Antibody Technique, Indirect Guinea Pigs Humans Intracellular Membranes - metabolism Intracellular Membranes - ultrastructure Microscopy, Electron Organelles - metabolism Protein Kinase C - antagonists & inhibitors Protein Kinase C - metabolism Recombinant Proteins - drug effects Recombinant Proteins - genetics Recombinant Proteins - metabolism Subcellular Fractions - metabolism Tetradecanoylphorbol Acetate - pharmacology Tumor Cells, Cultured
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