BEHAVIORAL EFFECTS OF FLUOXETINE IN AN ANIMAL MODEL OF ANXIETY/DEPRESSION ARE MEDIATED BY BOTH NEUROGENESIS-DEPENDENT AND INDEPENDENT MECHANISMS

Understanding the physiopathology of affective disorders and their treatment relies on the availability of experimental models that accurately mimic aspects of the disease. Here we describe a mouse model of an anxiety/depressive-like state induced by chronic corticosterone treatment. Furthermore, ch...

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Veröffentlicht in:Neuron (Cambridge, Mass.) Mass.), 2009-05, Vol.62 (4), p.479-493
Hauptverfasser: David, Denis J., Samuels, Benjamin Adam, Rainer, Quentin, Wang, Jing-Wen, Marsteller, Douglas, Mendez, Indira, Drew, Michael, Craig, Douglas A., Guiard, Bruno P., Guilloux, Jean-Philippe, Artymyshyn, Roman P., Gardier, Alain M, Gerald, Christophe, Antonijevic, Irina A., Leonardo, E. David, Hen, René
Format: Artikel
Sprache:eng
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