Regulation of ClC-1 and KATP channels in action potential-firing fast-twitch muscle fibers

Action potential (AP) excitation requires a transient dominance of depolarizing membrane currents over the repolarizing membrane currents that stabilize the resting membrane potential. Such stabilizing currents, in turn, depend on passive membrane conductance (G(m)), which in skeletal muscle fibers...

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Veröffentlicht in:	The Journal of general physiology 2009-10, Vol.134 (4), p.309-322
Hauptverfasser:	Pedersen, Thomas Holm, de Paoli, Frank Vincenzo, de Paoli, Frank Vinzenco, Flatman, John A, Nielsen, Ole Baekgaard
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials Animals Anthracenes - pharmacology Chloride Channels - metabolism Female KATP Channels - metabolism Membrane Potentials - physiology Muscle Fibers, Fast-Twitch - metabolism Patch-Clamp Techniques Rats Rats, Wistar Thermodynamics
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