Relevance of Biophysical Interactions of Nanoparticles with a Model Membrane in Predicting Cellular Uptake: Study with TAT Peptide-Conjugated Nanoparticles

The aim of the study was to test the hypothesis that the biophysical interactions of the trans-activating transcriptor (TAT) peptide-conjugated nanoparticles (NPs) with a model cell membrane could predict the cellular uptake of the encapsulated therapeutic agent. To test the above hypothesis, the bi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular pharmaceutics 2009-10, Vol.6 (5), p.1311-1320
Hauptverfasser:	Peetla, Chiranjeevi, Rao, Kavitha S, Labhasetwar, Vinod
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Transport, Active Biophysical Phenomena Cells, Cultured Drug Carriers - chemistry Drug Delivery Systems Endothelial Cells - metabolism Humans Membranes, Artificial Microscopy, Atomic Force Models, Molecular Nanoparticles - chemistry Nanotechnology Polyesters - chemistry Ritonavir - administration & dosage Static Electricity tat Gene Products, Human Immunodeficiency Virus - chemistry Thermodynamics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!