Proanthocyanidin from Blueberry Leaves Suppresses Expression of Subgenomic Hepatitis C Virus RNA

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease such as chronic hepatitis, cirrhosis, and hepatocellular carcinoma. While searching for new natural anti-HCV agents in agricultural products, we found a potent inhibitor of HCV RNA expression in extracts of blueberry leaves...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 2009-08, Vol.284 (32), p.21165-21176
Hauptverfasser:	Takeshita, Masahiko, Ishida, Yo-ichi, Akamatsu, Ena, Ohmori, Yusuke, Sudoh, Masayuki, Uto, Hirofumi, Tsubouchi, Hirohito, Kataoka, Hiroaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Blueberry Plants Chromatography, High Pressure Liquid Chromatography, Liquid - methods Drug Resistance, Viral Gene Expression Regulation, Viral - drug effects Hepacivirus - genetics Inhibitory Concentration 50 Mass Spectrometry - methods Neomycin - pharmacology Plant Extracts - metabolism Plant Leaves - metabolism Polymers - chemistry Proanthocyanidins - metabolism RNA, Viral RNA: Processing and Catalysis Virus Replication - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!