Brain atrophy rates predict subsequent clinical conversion in normal elderly and amnestic MCI

To test the hypothesis that the atrophy rate measured from serial MRI studies is associated with time to subsequent clinical conversion to a more impaired state in both cognitively healthy elderly subjects and in subjects with amnestic mild cognitive impairment (MCI). Ninety-one healthy elderly pati...

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Veröffentlicht in:	Neurology 2005-10, Vol.65 (8), p.1227-1231
Hauptverfasser:	JACK, C. R, SHIUNG, M. M, PETERSEN, R. C, WEIGAND, S. D, O'BRIEN, P. C, GUNTER, J. L, BOEVE, B. F, KNOPMAN, D. S, SMITH, G. E, IVNIK, R. J, TANGALOS, E. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Aged, 80 and over Aging - pathology Amnesia - diagnosis Amnesia - etiology Amnesia - physiopathology Atrophy - complications Atrophy - diagnosis Atrophy - physiopathology Biological and medical sciences Brain - pathology Brain - physiopathology Cohort Studies Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Disease Progression Entorhinal Cortex - pathology Entorhinal Cortex - physiopathology Female Hippocampus - pathology Hippocampus - physiopathology Humans Lateral Ventricles - pathology Lateral Ventricles - physiopathology Magnetic Resonance Imaging Male Medical sciences Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Neurology Predictive Value of Tests Time Factors
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