Floating drug delivery systems: a review
The purpose of writing this review on floating drug delivery systems (FDDS) was to compile the recent literature with special focus on the principal mechanism of floatation to achieve gastric retention. The recent developments of FDDS including the physiological and formulation variables affecting g...
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| Veröffentlicht in: | AAPS PharmSciTech 2005-10, Vol.6 (3), p.E372-E390 |
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| container_end_page | E390 |
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| container_issue | 3 |
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| container_title | AAPS PharmSciTech |
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| creator | Arora, Shweta Ali, Javed Ahuja, Alka Khar, Roop K Baboota, Sanjula |
| description | The purpose of writing this review on floating drug delivery systems (FDDS) was to compile the recent literature with special focus on the principal mechanism of floatation to achieve gastric retention. The recent developments of FDDS including the physiological and formulation variables affecting gastric retention, approaches to design single-unit and multiple-unit floating systems, and their classification and formulation aspects are covered in detail. This review also summarizes the in vitro techniques, in vivo studies to evaluate the performance and application of floating systems, and applications of these systems. These systems are useful to several problems encountered during the development of a pharmaceutical dosage form. |
| doi_str_mv | 10.1208/pt060347 |
| format | Article |
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| identifier | ISSN: 1530-9932 |
| ispartof | AAPS PharmSciTech, 2005-10, Vol.6 (3), p.E372-E390 |
| issn | 1530-9932 1530-9932 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Animals Dosage Forms Drug Carriers - administration & dosage Drug Carriers - pharmacokinetics Drug Delivery Systems - methods Gastrointestinal Agents - administration & dosage Gastrointestinal Agents - pharmacokinetics Gastrointestinal Tract - drug effects Gastrointestinal Tract - metabolism Humans Pharmaceutical Preparations - administration & dosage Pharmaceutical Preparations - metabolism |
| title | Floating drug delivery systems: a review |
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